The National Institute of Dental & Craniofacial Research (NIDCR), National Institutes of Health announced Tuesday that the California-based Center for Dental, Oral & Craniofacial Tissue & Organ Regeneration (C-DOCTOR) will be awarded $12 million over the next three years through a
A new large animal study from the Chai Lab at USC has been accepted by Stem Cells & Development. This publication describes the regenerative potential of cranial sutures in calvarial bone injury in swine. Park S, Zhao H, Urata M, Chai Y. (2016) Sutures
Park S, Zhao H, Urata M, Chai Y. (2016) Sutures possess strong regenerative capacity for calvarial bone injury. Stem Cells and Development. Accepted.
Wan DC, Siedhoff MT, Kwan MD, Nacamuli RP, Wu BM, Longaker MT. (2007) Refining retinoic acid stimulation for osteogenic differentiation of murine adipose-derived adult stromal cells. Tissue Eng. 13(7):1623-31. PMID17518707
Thank you to everyone from NorCal and SoCal who attended our latest planning meeting at UCSF’s Mission Bay complex. We are all very excited about the vision we all share for the mission and governance of the C-DOCTOR as we move
Lotz JC, Kroeber MW, Heilmann M, Pericherla K, Kimmel D, Kinney JH, Lane NE. (2000) Tibial plateau fracture as a measure of early estrogen-dependent bone fragility in rats. J Orthop Res. 18(2):326-32. PMID10815836
The suture provides a niche for mesenchymal stem cells of craniofacial bones. Zhao H, Feng J, Ho T-V, Grimes W, Urata M, & Chai Y. (2015) Nature Cell Biology doi:10.1038/ncb3139
Secretion of Shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor. Zhao H, Feng J, Seidel K, Shi S, Klein O, Sharpe P, Chai Y. (2014) Cell Stem Cell 14(2): 160-173. doi: 10.1016/j.stem.2013.12.013
Our kickoff meeting will be held on Saturday, November 7, 2015 in the Wentworth Room at the Langham Huntington in Pasadena, CA.
Our vision is to assemble a comprehensive and dynamic team of clinicians, research scientists, biostatisticians, regulatory scientists, and pre-clinical/clinical trial experts to enable the development and clinical implementation of innovative approaches for dental, oral, and craniofacial tissue regeneration. Read more